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   - January 7, 2009
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 Presentation

"The Link Between Diet, Exercise, and Insulin Resistance Reduction"

Dr. Stuart A Ross (biography)
English - 2005-10-21 - 36 minutes
(20 slides)

Summary :
In this presentation Dr. Ross talks about the importance of understanding the pathophysiology of type 2 diabetes, identifying the needs of the individual patient and tailoring their treatment accordingly to achieve optimal diabetes management.

Type 2 diabetes is characterised by impaired insulin secretion, as well as insulin resistance which can promote the development of cardiovascular disease through multiple associated abnormalities such as increased free fatty acids, TNF-alpha, PAI-1, leptin and resistin, and decreased adiponectin.

Results from the UKPDS indicated that diabetes is a progressive disease. Even with intensive treatment, HbA1c levels continued to rise (1). Some of the more modern treatment options available may be able to curb this deterioration in control. Dr. Ross reviews the 2003 CDA guidelines regarding the use of diet, exercise and pharmacotherapy for the treatment of overweight patients with mild to moderate hyperglycaemia.

Despite the availability of clear guidelines for the management of these patients, the DICE (Diabetes in Canada Evaluation) study recently demonstrated that a substantial proportion of type 2 diabetic patients have not achieved the target for glycaemic control. Dr. Ross discusses these findings and ends with some action points for the management of diabetic patients.

Copyright © 2005 E-MedHosting.com Inc.

Learning objectives :
After viewing this presentation the participant will be able to discuss:

- The pathophysiology of type 2 diabetes
- The progressive nature of type 2 diabetes
- Recent treatment guidelines from the Canadian Diabetes Association
- The state of glycaemic control in type 2 diabetic patients in Canada
- Action points for the management of diabetic patients

Bibliographic references :
1. UK Prospective Diabetes Study (UKPDS) GroupIntensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)Lancet. 1998 Sep 12;352(9131):837-53.

   


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